PG-931

Item no.	HY-P1208-100mg
Manufacturer	MedChem Express
CASRN	667430-81-1
Amount	100 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Purity	99.81
Citations	[1]D Giuliani, et al. Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage. Br J Pharmacol [2]P Grieco, et al. Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. J Pept Res
Smiles	O=C(N[C@@H](CCCCNC(C[C@@H](C(N1[C@](CCC1)([H])C(N[C@@H](C(N[C@H](C(N2)=O)CCCNC(N)=N)=O)CC3=CC=CC=C3)=O)=O)NC([C@@H](NC(C)=O)CCCC)=O)=O)C(N4[C@@H](CCC4)C(N[C@H](C(N)=O)C(C)C)=O)=O)[C@@H]2CC5=CNC6=CC=CC=C56
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Melanocortin Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Molecular Weight	1180.40
Product Description	PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R (IC50=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo[2].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	H2O : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	MC4R
Clinical information	No Development Reported

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HY-P1208-100mg-safety-datasheet.pdf