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COPS7B Peptide - middle region (AAP86595)

COPS7B Peptide - middle region (AAP86595)

Item no.	AAP86595
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Adenocarcinoma Astrocytoma Peptides By Organ Bladder Cancer Breast Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CSN7B,SGN7b
Available
Manufacturer - Type	Blocking Peptide
Molecular Weight	30 kDa
Description	This is a synthetic peptide designed for use in combination with anti- COPS7B Antibody (ARP86595_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	COPS7B
Protein size	273
Product format	Lyophilized powder
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Nucleotide accession_num	NM_001282950.2
Protein accession_num	NP_001269879.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/8/2026

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