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HDAC5 Peptide - middle region (AAP87413)

HDAC5 Peptide - middle region (AAP87413)

Item no.	AAP87413
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Neural Epigenetics By Cell Type Melanoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	HD5,NY-CO-9
Available
Manufacturer - Type	Blocking Peptide
Molecular Weight	114 kDa
Description	This is a synthetic peptide designed for use in combination with anti- HDAC5 Antibody (ARP87413_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	HDAC5
Protein size	1037
Product format	Lyophilized powder
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
Nucleotide accession_num	NM_001015053.1
Protein accession_num	NP_001015053.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AAP87413-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 12/25/2025

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