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PMAIP1 Peptide - middle region (AAP89773)

PMAIP1 Peptide - middle region (AAP89773)

Item no.	AAP89773
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Cell Biology Cell Status Apoptosis Adenocarcinoma Autophagy Astrocytoma Peptides By Organ Breast Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Noxa
Available
Manufacturer - Type	Blocking Peptide
Molecular Weight	11 kDa
Description	This is a synthetic peptide designed for use in combination with anti- PMAIP1 Antibody (ARP89773_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	PMAIP1
Protein size	103
Product format	Lyophilized powder
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1.
Nucleotide accession_num	NM_021451.2
Protein accession_num	NP_067426.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AAP89773-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 12/25/2025

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