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NGEF Peptide - C-terminal region (AAP92263)

NGEF Peptide - C-terminal region (AAP92263)

Item no.	AAP92263
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Peptides & Proteins Cell Biology Cytoskeleton Peptides small GTPases Rho Subfamily
Type	Peptides
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Tims2,ephexin
Available
Manufacturer - Type	Blocking Peptide
Molecular Weight	71 kDa
Description	This is a synthetic peptide designed for use in combination with anti- NGEF Antibody (ARP92263_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	NGEF
Protein size	620
Product format	Lyophilized powder
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension.
Nucleotide accession_num	NM_001111314.1
Protein accession_num	NP_001104784.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AAP92263-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 12/25/2025

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