Mouse bFGF protein

Cytokine

bFGF

Lyophilized Mouse bFGF proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.4% HSA or BSA). Please prevent freeze-thaw cycles.

Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.

Lyophilized from sterile 400mM NaCl 20mM PB , pH 7.0.

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse bFGF protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.2 ng/mL.

BFGF, FGF-2, FGFB, HBGF-2, Fibroblast growth factor 2, FGF2