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(Ser(PO₃H₂)²⁷³)-Nek11 (268-283) trifluor

(Ser(PO₃H₂)²⁷³)-Nek11 (268-283) trifluor

Item no.	BAC-4104897.0500
Manufacturer	Bachem
CASRN	2243207-06-7
Amount	0,5 MG
Quantity options	0,5 MG
Category	Oncology Peptides & Proteins Peptides By Organ Colorectal Cancer
Type	Peptides
Specific against	other
Formula	C₇₇H₁₃₅N₂₂O₂₆PS
Sequence	H-Leu-Asn-Lys-Asn-Pro-Ser(PO₃H₂)-Leu-Arg-Pro-Ser-Ala-Ile-Glu-Ile-Leu-Cys-OH
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Room temperature
Available
Manufacturer - Category	Biochemical Reagents
Manufacturer - Targets	EPHA7
Shipping Temperature	Ambient Temperature
Storage Conditions	< -15℃
Molecular Weight	1848.09
Description	Depletion of NEK11 prevents proteasome-dependent degradation of CDC25A, both in unperturbed and DNA-damaged cells. In addition, NEK11 directly phosphorylates CDC25A, and CHK1 (checkpoint kinase 1) directly activates NEK11 by phosphorylating it on Ser²7³. Taken together, NEK11 is an important component of the pathway enforcing the G2/M checkpoint, and genetic mutations in NEK11 may contribute to the development of cancer. These results have been shown by Melixetian and coworkers.
Num Amino Acids	16
Salt	Trifluoroacetate

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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