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Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein, Twin-Streptavidin Tag&Tag Free European Partner

Item no. IT1-H5283-100ug
Manufacturer ACROBiosystems
Amount 100 ug
Quantity options 100 ug 500 ug x 2
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Unconjugated, Twin-Streptavidin
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-Twin-streptavidin | Native, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
116.4 kDa & 83.7 kDa
Manufacturer - Format
Powder
Description
Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.
Background
Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.
Molecule
Integrin alpha 8 beta 1
Exp Region
Phe 39 - Leu 1012 & Gln 21 - Asp 728
Characteristics
Human ITGA8&ITGB1 Heterodimer Protein, Twin-Streptavidin Tag&Tag Free, produced by co-expression of ITGA8 and ITGB1, has a calculated MW of 116.4 kDa (ITGA8) and 83.7 kDa (ITGB1). Subunit ITGA8 is fused with streptavidin II-tag at the C-terminus and subunit ITGB1 contains no tag. The protein migrates as 150-180 kDa (ITGA8) and 95-110 kDa (ITGB1) when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
50 mM Tris, 150 mM NaCl, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Delivery expected until 2/12/2026 

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