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[Novoprotein] Recombinant Mouse Dickkopf-Related Protein 1/mDKK1/DKK-1 (N-8His)

Item no. NOVP-C773-50ug
Manufacturer Novoprotein Scientific
Amount 50 ug
Quantity options 10 ug 1 mg 500 ug 50 ug
Category
Type Proteins Recombinant
Format Lyophilized
Specific against Mouse (Murine, Mus musculus)
Host Human
Conjugate/Tag HIS
Purity Greater than 95% as determined by reducing SDS-PAGE.
Sequence HHHHHHHHQTLNSVLINSNAIKNLPPPLGGAGGQP GSAVSVAPGVLYEGGNKYQTLDNYQPYPCAEDEEC GSDEYCSSPSRGAAGVGGVQICLACRKRRKRCMRH AMCCPGNYCKNGICMPSDHSHFPRGEIEESIIENL GNDHNAAAGDGYPRRTTLTSKIYHTKGQEGSVCLR SSDCAAGLCCARHFWSKICKPVLKEGQVCTKHKRK GSHGLEIFQRCYCGEGLACRIQKDHHQASNSSRLH TCQ
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Dickkopf-related protein 1,Dickkopf-1,Dkk-1,mDkk-1,Dkk1
Shipping Condition Room temperature
Available
Shipping Temperature
The product is shipped at ambient temperature.
Storage Conditions
Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.
Molecular Weight
27, 4
Description
Recombinant Mouse Dickkopf-related protein 1 is produced by our Mammalian expression system & the target gene encoding Thr32-His272 is expressed with a 8His tag at the N-terminus.
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Background
This gene encodes a protein that is a member of the dickkopf family. It possesses two clusters of ten cysteine residues separated by a linker region. The protein highly expressed in thyroid, small intestine, stomach, liver, placenta, pancreas, uterus, abdominal cavity, bladder & skin. Weaker expression has been detected in colon & spleen. It antagonizes canonical Wnt signaling by inhibiting LRP5/6interaction with Wnt & by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Sequence Length
Thr32-His272

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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