Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 (C-6His)

Store at < -20C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Recombinant Human FBPase 1 is produced by our Mammalian expression system & the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus.

Fructose-1, 6-bisphosphatase 1(FBP1) is a homotetramer protein & belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1, 6-bisphosphate to fructose 6-phosphate & inorganic phosphate. FBP1 deficiency is associated with hypoglycemia & metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.