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CCL2 Protein

CCL2 Protein

Item no.	OPCB00010
Manufacturer	AVIVA Systems Biology
Amount	5 ug
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	> 97% as determined by SDS-PAGE
Sequence	The protein sequence is: <a href='//www.ncbi.nlm.nih.gov/blast/Blast.cgi?PROGRAM=blastp&CLIENT=web&SERVICE=plain&PAGE=Proteins&CMD=Put&DATABASE=nr&CDD_SEARCH=1&AUTO_FORMAT=Semi-auto&SHOW_OVERVIEW=on&SHOW_LINKOUT=on&GET_SEQUENCE=on&NCBI_GI=on&ALIGNMENTS=50
Citations	1. "Monocyte Chemoattractant Protein-1 (MCP-1): An Overview" Deshmane S., Kremlev S., Amini S., Sawaya B. J Interferon Cytokine Res. 29: 313â€“326 (2009) 2. "Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE" Yoshimura T., Yuhki N., Moore S. K., Appella E., Lerman M. I., Leonard E. J. FEBS Letters 244: 487â€“493 (1989) 3. "Monocyte chemoattractant protein-1: A key mediator in inflammatory processes" Melgarejo E., Medina M., SÃ¡nchez-JimÃ©nez F., Urdiales J. Int J Biochem Cell Biol 41: 998-1001 (2009)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	HC11,MCAF,MCP1,MCP-1,SCYA2,GDCF-2,SMC-CF,HSMCR30
Shipping Condition	Cool pack
Available
Manufacturer - Type	Protein
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Shipping Temperature	Wet Ice
Molecular Weight	8.662 kDa
Gene symbol	CCL2
Gene Fullname	chemokine (C-C motif) ligand 2
Product format	Lyophilized
Reconstitution and storage	Spin tube prior to resuspending. Recommended at 100ug/mL in sterile water Shipping: Room Temp
Description of target	Monocyte chemoattractant protein-1 (MCP-1) (CCL2) is produced by many cell types at sites of inflammation. It regulates chemotaxis and transendothielial migration of monocytes, as well as memory T cells and natural killer cells by interacting with their membrane surface receptor CCR2. MCP-1 has also been implicated in a number of disease states, such as rheumatoid arthritis, atherosclerosis, autoimmune diseases, tumor progression, and HIV infection.
Biological activity	EC50 = 0.067nM determined by Migration Assay of recombinant CCR2 containing cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 ug

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Delivery expected until 12/25/2025

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