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NR1H2 Recombinant Protein

NR1H2 Recombinant Protein

Item no.	OPCD00379
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins Obesity Immunoprecipitation Western Blot ELISA Lipoprotein Receptors & Associated Proteins SDS-PAGE
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI194859;liver X receptor beta;LX;LXR;LXR beta;LXRB;LXRbeta;LXRBSV;NER1;Nuclear receptor subfamily 1 group H member 2;OR-1;oxysterols receptor LXR-beta;retinoid X receptor-interacting protein No.15;RI;RIP15;Ubiquitously-expressed nuclear receptor;ubiquitously-expressed nuclear receptor 2;Un;Unr;Unr2;UR.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	50kDa
Gene symbol	Nr1h2
Gene Fullname	nuclear receptor subfamily 1, group H, member 2
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:18055760, PubMed:19520913, PubMed:20427281). Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4) (PubMed:18055760, PubMed:19520913, PubMed:20427281). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8 (PubMed:18055760, PubMed:19520913, PubMed:20427281). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (PubMed:18055760, PubMed:19520913, PubMed:20427281). Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (By similarity).
Nucleotide accession_num	NM_001285517.1
Protein accession_num	NP_001272446.1
Protein name	Oxysterols receptor LXR-beta
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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