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PPP1R15A Recombinant Protein

PPP1R15A Recombinant Protein

Item no.	OPCD00533
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Neuroinflammation By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Adenocarcinoma Mesothelioma Immunoprecipitation Western Blot ELISA SDS-PAGE Astrocytoma By Organ Colorectal Cancer Breast Cancer
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	9630030H21;Gadd3;Gadd34;growth arrest and DNA damage-inducible protein GADD34;growth arrest and DNA-damage-inducible 34;Myd116;myeloid differentiation primary response gene 116;myeloid differentiation primary response protein MyD116;protein phosphatase 1 regulatory subunit 15A;protein phosphatase 1,regulatory (inhibitor) subunit 15A.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	33kDa
Gene symbol	Ppp1r15a
Gene Fullname	protein phosphatase 1, regulatory subunit 15A
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. In case of infection with vesicular stomatitis virus (VSV), impairs viral replication.
Nucleotide accession_num	NM_008654.2
Protein accession_num	NP_032680.1
Protein name	Protein phosphatase 1 regulatory subunit 15A
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD00533-datasheet.pdf

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Amount: 10 ug

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Delivery expected until 12/25/2025

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