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ERLIN2 Recombinant Protein

ERLIN2 Recombinant Protein

Item no.	OPCD00700
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE Enzymes Fatty Acid Synthesis
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Conjugate/Tag	Unconjugated; HIS
Purity	> 90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	C8orf2;endoplasmic reticulum lipid raft-associated protein 2;epididymis secretory sperm binding protein;erlin-2;NET32;spastic paraplegia 18 (autosomal dominant);SPFH domain family,member 2;SPFH2;SPG18;stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	37kDa
Gene symbol	ERLIN2
Gene Fullname	ER lipid raft associated 2
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
Nucleotide accession_num	NM_001003790.3
Protein accession_num	NP_001003790.1
Protein name	Erlin-2
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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