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AATF Recombinant Protein

AATF Recombinant Protein

Item no.	OPCD00997
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Metabolism Diabetes Aging & Neurological Disorders Neural Epigenetics By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Immunoprecipitation Western Blot ELISA SDS-PAGE Senescence Astrocytoma By Organ Lung Cancer Bladder Cancer Bone Cancer
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS, GST
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	4933415H02Rik;5830465M17Rik;Apoptosis-antagonizing transcription factor;Che-1;protein AATF;rb-binding protein Che-1;Tr;traube protein;Trb.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His and GST Tag
Molecular Weight	53kDa
Gene symbol	Aatf
Gene Fullname	apoptosis antagonizing transcription factor
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression (By similarity).
Nucleotide accession_num	NM_019816.1
Protein accession_num	NP_062790.1
Protein name	Protein AATF
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD00997-datasheet.pdf

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Amount: 10 ug

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Delivery expected until 10/30/2025

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