FIGN Recombinant Protein

Protein

Root Catalog/Products/Recombinant Proteins

41kDa

fidgetin, microtubule severing factor

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome.

NP_060556.2

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.