GRB7 Recombinant Protein

Protein

Root Catalog/Products/Recombinant Proteins

33kDa

growth factor receptor bound protein 7

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).

NP_001025173.1

200 ug/mL (prior to lyoph)