HLTF Recombinant Protein

Protein

Root Catalog/Products/Recombinant Proteins

21.4kDa

helicase-like transcription factor

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA (By similarity).

NP_033236.2

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.