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IGF1 Recombinant Protein

IGF1 Recombinant Protein

Item no.	OPCD04169-50UG
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Cell Status Adenocarcinoma Mesothelioma Immunoprecipitation Western Blot ELISA Autophagy Endocrine Regulation of Lipid Metabolism SDS-PAGE Cardiovascular Research Proliferation Myocardial Infarction
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Chicken (Gallus gallus domesticus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS, GST
Purity	> 90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IGF-1;IGF-I;insulin-like growth factor 1 (somatomedin C);insulin-like growth factor I;somatomedin.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His and GST Tag
Molecular Weight	44.1kDa
Gene symbol	IGF1
Gene Fullname	insulin like growth factor 1
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.
Nucleotide accession_num	NM_001004384.2
Protein accession_num	NP_001004384.1
Protein name	Insulin-like growth factor I
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD04169-50UG-datasheet.pdf

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Amount: 50 ug

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Delivery expected until 12/25/2025

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