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ITGB4 Recombinant Protein

ITGB4 Recombinant Protein

Item no.	OPCD04598
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Neural Signaling By Cell Type Carcinoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Adenocarcinoma Immunoprecipitation Western Blot ELISA Endocrine Regulation of Lipid Metabolism SDS-PAGE Neuronal Cell Markers
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AA407042;C230078O20;CD104;integrin beta-4.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	37kDa
Gene symbol	Itgb4
Gene Fullname	integrin beta 4
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.
Nucleotide accession_num	XM_006532572.3
Protein accession_num	XP_006532635.1
Protein name	Integrin beta-4
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 10/30/2025

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