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WWC1 Recombinant Protein

WWC1 Recombinant Protein

Item no.	OPCD04659
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Mesothelioma Immunoprecipitation Western Blot ELISA SDS-PAGE By Organ Lung Cancer Bladder Cancer Breast Cancer
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 97%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AA408228;AU017197;BC037006;Ki;Kibra;kidney and brain protein;protein KIBRA;protein WWC1;WW domain-containing protein 1.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	40kDa
Gene symbol	Wwc1
Gene Fullname	WW, C2 and coiled-coil domain containing 1
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ and may be associated with memory performance (By similarity). Regulates collagen-stimulated activation of the ERK/MAPK cascade.
Nucleotide accession_num	NM_170779.1
Protein accession_num	NP_740749.1
Protein name	Protein KIBRA
Formulation	100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 1/8/2026

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