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MMP14 Recombinant Protein

MMP14 Recombinant Protein

Item no.	OPCD05324
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Conjugate/Tag	Unconjugated; HIS
Purity	> 90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI325305;matrix metalloproteinase 14 (membrane-inserted);matrix metalloproteinase-14;Membrane type 1-MMP;Membrane-type matrix metalloproteinase 1;membrane-type-1 matrix metalloproteinase;MMP-X1;MT1-MM;MT1-MMP;MT-MMP;MT-MMP-1;sa;sabe;type 1 matrix metalloprotease 14.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	44kDa
Gene symbol	Mmp14
Gene Fullname	matrix metallopeptidase 14 (membrane-inserted)
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (PubMed:10520996). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (By similarity). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues (By similarity). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (By similarity).
Nucleotide accession_num	NM_008608.4
Protein accession_num	NP_032634.3
Protein name	Matrix metalloproteinase-14
Formulation	20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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