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PLA2G2A Recombinant Protein

PLA2G2A Recombinant Protein

Item no.	OPCD06245
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Adhesion Molecules By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Immunoprecipitation Western Blot ELISA SDS-PAGE Enzymes Fatty Acid Catabolism
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GIIC sPLA2;group IIA phospholipase A2;MOM1;non-pancreatic secretory phospholipase A2;NPS-PLA2;phosphatidylcholine 2-acylhydrolase 2A;phospholipase A2,group IIA (platelets,synovial fluid);phospholipase A2,membrane associated;PLA2;PLA2B;PLA2L;PLA2S;PLAS1;sPLA2.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	18kDa
Gene symbol	PLA2G2A
Gene Fullname	phospholipase A2 group IIA
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Nucleotide accession_num	NM_000300.3
Protein accession_num	NP_000291.1
Protein name	Phospholipase A2, membrane associated
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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