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PRTN3 Recombinant Protein

PRTN3 Recombinant Protein

Item no.	OPCD06362
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ACPA;AGP7;azurophil granule protein 7;CANCA;C-ANCA;C-ANCA antigen;leukocyte proteinase 3;MBN;MBT;myeloblastin;neutrophil proteinase 4;NP4;NP-4;P29;PR3;PR-3;serine proteinase,neutrophil;wegener autoantigen;Wegener granulomatosis autoantigen.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	21/17kDa
Gene symbol	PRTN3
Gene Fullname	proteinase 3
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279).
Nucleotide accession_num	NM_002777.3
Protein accession_num	NP_002768.3
Protein name	Myeloblastin
Formulation	20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Concentration	50 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD06362-datasheet.pdf

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Amount: 10 ug

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Delivery expected until 12/25/2025

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