« Back
Home /
SIGIRR Recombinant Protein

SIGIRR Recombinant Protein

Item no.	OPCD06970
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Rat (Rattus norvegicus)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	RGD1306732;single Ig IL-1-related receptor;single Ig IL-1R-related molecule;single immunoglobulin and toll-interleukin 1 receptor (TIR) domain;single immunoglobulin domain-containing IL1R-related protein;TIR8;toll/interleukin-1 receptor 8.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	17kDa
Gene symbol	Sigirr
Gene Fullname	single Ig and TIR domain containing
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).
Nucleotide accession_num	NM_001024887.1
Protein accession_num	NP_001020058.1
Protein name	Single Ig IL-1-related receptor
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OPCD06970-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 10 ug

available

Delivery expected until 12/25/2025

Express Delivery: Save 2 days

Compare

Add to wishlist

Get an offer