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TICAM2 Recombinant Protein

TICAM2 Recombinant Protein

Item no.	OPCD07438
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation By Cell Type Hematology Leukemia Lymphoma Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Unconjugated; HIS
Purity	> 97%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	cytoplasmic adaptor;MyD88-4;NF-kappa-B-activating protein 502;putative NF-kappa-B-activating protein 502;TICAM2;TICAM-2;TIR domain-containing adapter molecule 2;TIRAP3;TIRP;TMED7-TICAM2 read-through transcript;toll/interleukin-1 receptor (TIR) domain-containing adapter protein;Toll/interleukin-1 receptor domain-containing protein;toll-like receptor adaptor protein 3;TRAM;TRAM adaptor with GOLD domain;TRIF-related adapter molecule;TRIF-related adaptor molecule.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Molecular Weight	34kDa
Gene symbol	TICAM2\|TMED7-TICAM2
Gene Fullname	TMED7-TICAM2 readthrough\|toll like receptor adaptor molecule 2
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 signaling during adaptive immune response.
Nucleotide accession_num	NM_001164468.3
Protein accession_num	NP_001157940.1
Protein name	TIR domain-containing adapter molecule 2
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD07438-datasheet.pdf

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Amount: 10 ug

available

Delivery expected until 10/30/2025

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