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TNFRSF11B Recombinant Protein

TNFRSF11B Recombinant Protein

Item no.	OPCD08039
Manufacturer	AVIVA Systems Biology
Amount	10 ug
Category	Oncology Metabolism Glucose Homeostasis Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Immunoprecipitation Western Blot ELISA SDS-PAGE By Organ Lymphatic System Cancer
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	Human (Homo sapiens)
Host	293F Cells
Conjugate/Tag	Unconjugated; HIS
Purity	> 95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	OCIF;OPG;osteoclastogenesis inhibitory factor;osteoprotegerin;PDB5;TR1;tumor necrosis factor receptor superfamily member 11B;tumor necrosis factor receptor superfamily,member 11b.
Available
Manufacturer - Type	Protein
Manufacturer - Applications	Positive control\|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis\|Western blot
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Manufacturer - Conjugate / Tag	N-terminal His Tag
Manufacturer - Host	293F cell
Molecular Weight	42kDa
Gene symbol	TNFRSF11B
Gene Fullname	TNF receptor superfamily member 11b
Protein size	Recombinant
Product format	Freeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.
Reconstitution and storage	2°C to 8°C\|-80°C
Description of target	Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Nucleotide accession_num	NM_002546.3
Protein accession_num	NP_002537.3
Protein name	Tumor necrosis factor receptor superfamily member 11B
Formulation	20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
Concentration	200 ug/mL (prior to lyoph)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 12/25/2025

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