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TNFSF10 Recombinant Protein (Mouse)

TNFSF10 Recombinant Protein (Mouse)

Item no.	OPED00144
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Metabolism Glucose Homeostasis Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	E.coli
Purity	>95% (SDS-PAGE)
Dry ice	Yes
Citations	Targeting Immune Privilege to Prevent Pathogenic Neovascularization: J. Roychoudhury, et al.; Invest. Ophthalmol. Vis. Sci. 51, 3560 (2010), Application(s): Intravitreal injections in mice for studies on choroidal neovascularization, Abstract; Full Text Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells: A. Lundqvist, et al.; Blood 113, 6120 (2009), Application(s): Death induction of sensitized Renca cells, Abstract; Full Text IRF-5 Is a Mediator of the Death Receptor-induced Apoptotic Signaling Pathway: G. Hu & B.J. Barnes; J. Biol. Chem. 284, 2767 (2009), Application(s): Death induction of HCT116 cells, Abstract; Full Text Treating Metastatic Solid Tumors With Bortezomib and a Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor Agonist Antibody: A. Shanker, et al.; J. Natl. Cancer Inst. 100, 649 (2008), Application(s): Death induction of sensitized Renca, TBJ, 4T1 cells, Abstract; Full Text The role of NF-kappa B-1 and NF-kappa B-2-mediated resistance to apoptosis in lymphomas: L. Bernal-Mizrachi, et al.; PNAS 103, 9220 (2006), Application(s): Death induction of 204-3-1, NK-H and NK-92 cells and analysis of resistance to TRAIL-induced cell death of Daudi, SC, F8 and BLA cells, Abstract; Full Text Keratins Modulate c-Flip/Extracellular Signal-Regulated Kinase 1 and 2 Antiapoptotic Signaling in Simple Epithelial Cells: S. Gilbert, et al.; Mol. Cell Biol. 24, 7072 (2004), Application(s): Death induction of sensitized mouse primary hepatocytes, Abstract; Full Text TRAIL and KILLER Are Expressed and Induce Apoptosis in the Murine Preimplantation Embryo: J.K. Riley, et al.; Biol. Reprod. 71, 871 (2004), Application(s): Death induction of sensitized mice blastocysts, Abstract; Full Text The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP: T.J. Sayers, et al.; Blood 102, 303 (2003), Application(s): Death induction of sensitized C1498 and Renca cells and sensitized C1498-bone marrow cocultures in mice, Abstract; Full Text Roles of TNF-Related Apoptosis-Inducing Ligand in Experimental Autoimmune Encephalomyelitis: B. Hilliard, et al.; J. Immunol. 15, 166 (2001), Application(s): Death induction of L929 cells, Abstract; Full Text
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Apo-2 ligand;Apo-2L;APO2L;CD253;chemokine tumor necrosis factor ligand superfamily member 10;TL2;TNF-related apoptosis inducing ligand TRAIL;TNF-related apoptosis-inducing ligand;TNLG6A;TRAIL;tumor necrosis factor (ligand) family,member 10;tumor necrosis factor (ligand) superfamily,member 10;tumor necrosis factor apoptosis-inducing ligand splice variant delta;tumor necrosis factor ligand 6A;tumor necrosis factor ligand superfamily member 10;tumor necrosis factor superfamily member 10.
Shipping Condition	Dry ice
Available
Manufacturer - Type	Protein
Manufacturer - Category	Root Catalog/Products/Recombinant Proteins
Shipping Temperature	Dry Ice
Molecular Weight	23 kDa
Gene symbol	TNFSF10
Gene Fullname	TNF superfamily member 10
Protein size	Recombinant
Product format	Liquid. In PBS containing 0.1mM DTT.
Reconstitution and storage	Store at -80C
Description of target	Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:26457518, PubMed:10549288). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Protein name	Tumor necrosis factor ligand superfamily member 10
Purification	Purified by multi-step chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/25/2025

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