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ZIP acetate(863987-12-6 free base)

ZIP acetate(863987-12-6 free base)

Item no.	TMO-TP1924L1-500mg
Manufacturer	TargetMol
Amount	500 mg
Quantity options	100 mg 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Peptides & Proteins Enzymes
Type	Enzymes
Specific against	other
Smiles	CCCCCCCCCCCCCC(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O.CC(=O)O
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PKC
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	1988.43
Description	ZIP acetate is a novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo.
Pathways	Cytoskeletal Signaling\|\|\|Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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