IFNL2, Recombinant, Human (Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A, IL28A, ZCYTO20)

Molecular Biology / MB-Growth Factors-Interferon

-20°C

Supplied as a lyophilized powder.

IFN -u-1, -2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-uR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant human IFN-lamda 2 is a 19.6kD protein containing 174aa.

Source:
Recombinant protein corresponding to IFN lamda 2, expressed in E.coli.

Biological Activity:
Determined by its ability to activate STAT following receptor-ligand interaction.

Endotoxin:
<0.1ng/ug (1EU/ug)

AA Sequence:
PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.