CD274, Recombinant, Mouse, aa19-239, His-Tag (PD-L1, Programmed Cell Death 1 Ligand Protein 1, PDCD1 Ligand 1, B7-H1, PDL1)

Blue Ice

27, 6

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 10% glycerol.

CD274, also known as programmed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interacts with PDCD1 inhibits T-cell proliferation and cytokine production.

Source:
Recombinant protein corresponding to aa19-239 of mouse CD274, fused to His-tag at N-terminal expressed in E. coli.

Molecular Weight:
~27.6kD

Amino Acid Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMFTITA PKDLYVVEYG SNVTMECRFP VERELDLLAL VVYWEKEDEQ VIQFVAGEED LKPQHSNFRG RASLPKDQLL KGNAALQITD VKLQDAGVYC CIISYGGADY KRITLKVNAP YRKINQRISV DPATSEHELI CQAEGYPEAE VIWTNSDHQP VSGKRSVTTS RTEGMLLNVT SSLRVNATAN DVFYCTFWRS QPGQNHTAEL IIPELPATHP PQNRTH

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.