FABP4, Recombinant, Human, aa1-132 (Fatty Acid Binding Protein 4)

Blue Ice

14

Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 2mM EDTA, 10% glycerol.

FABP4 (Fatty acid binding protein 4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. FABP4 is thought to regulate fatty acid uptake, release, and storage in adipocytes and participates in systemic glucose homeostasis and in macrophage responses in atherosclerosis. Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease, diabetes, asthma, obesity, and fatty liver disease.

Recombinant protein corresponding to aa1-132 of human FABP4 expressed in E. coli.

Molecular Weight:
~14kD (132aa), confirmed by MALDI-TOF

Amino Acid Sequence:
MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDVI TIKSESTFKN TEISFILGQE FDEVTADDRK VKSTITLDGG VLVHVQKWDG KSTTIKRKRE DDKLVVECVM KGVTSTRVYE RA

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.