SNRPC, Recombinant, Human, aa1-159, His-Tag (u1 Small Nuclear Ribonucleoprotein C)

Blue Ice

19, 8

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.3M sodium chloride, 5mM DTT, 2mM EDTA, 50% glycerol.

SNRPC belongs to the u1 small nuclear ribonucleoprotein C family. This protein component of the u1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. This protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases.

Recombinant protein corresponding to aa1-159 of human SNRPC, fused to His-Tag at N-terminal, expressed in E. coli. Accession Number: NP_003084

Molecular Weight:
~19.8kD (182aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence:
MPKFYCD YCDTYLTHDS PSVRKTHCSG RKHKENVKDY YQKWMEEQAQ SLIDKTTAAF QQGKIPPTPF SAPPPAGAMI PPPPSLPGPP RPGMMPAPHM GGPPMMPMMG PPPPGMMPVG PAPGMRPPMG GHMPMMPGPP MMRPPARPMM VPTRPGMTRP DR

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.