TNFRSF11A, Recombinant, Human, aa28-212, HIgG-His-Tag (TNFRSF11A, CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER)

Blue Ice

47, 6

Supplied as a liquid in PBS, pH 7.4, 10% glycerol.

TNFRSF11A, also known as tumor necrosis factor receptor superfamily member 11A, is a member of the tumor necrosis factor receptor family. TNFRSF11A is widely expressed with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland and dendritic cells. In activated human peripheral blood T lymphocytes, TNFRSF11A expression is induced by IL4 and TGF-b.

Source:
Recombinant protein corresponding to aa28-212 from human TNFRSF11A, fused to His-tag at C-terminal expressed in Insect cell.

Molecular Weight:
~47.6kD (427aa)

Amino Acid Sequence:
ADPLQIAPPC TSEKHYEHLG RCCNKCEPGK YMSSKCTTTS DSVCLPCGPD EYLDSWNEED KCLLHKVCDT GKALVAVVAG NSTTPRRCAC TAGYHWSQDC ECCRRNTECA PGLGAQHPLQ LNKDTVCKPC LAGYFSDAFS STDKCRPWTN CTFLGKRVEH HGTEKSDAVC SSSLPARKPP NEPHVYLPLE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPGKHHHHHH

Endotoxin: ~1EU/1ug (LAL)

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.