HSPA5, Recombinant, Human, aa25-293, His-Tag (78kD Glucose-regulated Protein, Endoplasmic Reticulum Chaperone BiP, Heat Shock Protein 70 Family Protein 5)

Blue Ice

33, 6

Supplied as a liquid in Tris, 50% glycerol.

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

Partial recombinant protein corresponding to aa25-293 from human HSPA5, fused to 6xHis-Tag at N-terminal, expressed in E. coli. Uniprot/Swiss Accession: P11021

Molecular Weight:
~33.6kD

Amino Acid Sequence:
EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVE

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.