Aprotinin, Bovine (New Zealand) (Pancreatic trypsin inhibitor)

RT

6500

White lyophilized powder

Aprotinin is a broad spectrum serine protease inhibitor used in diagnostics applications to prevent proteolytic degradation. It exhibits high specific activity against trypsin, chymotrypsin, plasmin and kallekrein. Used in diagnostic systems to prevent proteolytic damage in downstream purification of proteins and serum-free media.

Synonyms:
Antikrein; Antilysin; Antilysine; Aprostat; Aprotinin; BPTI; BPTI Trypsin Inhibitor; Basic Pancreatic Trypsin Inhibitor; Bayer A 128; Bovine Basic Pancreatic Trypsin Inhibitor; Bovine Pancreatic Trypsin Inhibitor; Bovine Trypsin Inhibitor; Fosten; Kallikrein-trypsin Inactivator; Kiker 52G; Kir Richter; Kunitz Pancreatic Trypsin Inhibitor; Kunitz Protease Inhibitor; Kunitz Trypsin Inhibitor; Kunitz-type Inhibitor; Kunitz-type Proteinase Inhibitor; Kunitz-type Trypsin Inhibitor; Onquinin; Pancreatic Basic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor (Kunitz); Protease Inhibitor, Kunitz Type; RP 9921; Repulson; Trasuylol; Trasylol; Trazinin; Triazinin; Trypsin Inhibitor, Trasylol; Trypsin-kallikrein Inhibitor (Kunitz); Zymofren

CAS No:
9087-70-1

Molecular Weight:
~6500

Source:
Bovine Lung

Appearance:
White lyophilized powder

Purity:
≥98%

Endotoxin:
≤10Eu/mg

Protein:
≥80-99%

Activity:
5500-7400KIU/mg

Unit Definition:
One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze one micromole of Na-benzoyl-DL-arginine-p-nitroanilide (BAPNA) per minute at pH 7.8, 25°C.

Working Concentration:
0.04-2ug/ml

pH (1%):
5.0-7.0

Moisture:
≤6%

Ash:
≤5%

Sodium:
≤50mg/g

Virus Testing (BVD, IBR, P13; 5 passages):
Negative

Certificate of Origin:
All raw material used in the manufacturing of Aprotinin is of New Zealand origin. The animals used received both ante and post mortem inspections under certified veterinary care and were inspected to be free of apparent infectious and contagious diseases. BSE (Bovine Spongiform Encephalopathy) is not known to exist in the New Zealand. The age of the bovine raw material is less than 3 years.