Bestatin Hydrochloride

Blue Ice

344, 83

White powder

A metallo-protease inhibitor. Inhibits aminopeptidase B, leucine aminopeptidase and leukotriene A4 hydrolase. Inhibits enkephalin degradation in cell preparations from brain. Does not inhibit carboxypeptidases.

Sequence:
[(2S, 3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine

CAS No:
65391-42-6

Molecular Formula:
C16H24N2O4.HCl

Molecular Weight:
344.83

Appearance:
White powder

Purity:
~95% (HPLC)

Melting Point:
213-215°C

Carbon, Anhydrous (%):
54.6-56.9%

Nitrogen, Anhydrous (%):
8.0-8.3%

Chloride, Anhydrous (%):
10.0-10.6%

Moisture (Karl Fischer):
≤6%

Solubility:
Soluble in methanol and acetic acid.
Colorless, clear to slightly hazy at 25mg/ml in water

Storage and Stability:
Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. Protect from light.