Comparison

MLN4924 (Pevonedistat)

Item no. RPE-CV-1006-1
Manufacturer rPeptide
Amount 1.0 mg
Quantity options 1.0 mg 5.0 mg
Category
Type Inhibitors
Format Solid
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Category
COVID-19/ Small Molecules
Shipping Temperature
Ambient
Storage Conditions
-20°C
Description
Potent and selective NEDD8-activating enzyme (NAE) inhibitor. It disrupts cullin-RING ligasemediated protein turnover leading to apoptosis in human tumor cells. Suppresses the growth of human tumor xenografts in mice. Upregulates PD-L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma. Modulates tumor microenvironment. Cell permeable.
Physical State
White powder

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1.0 mg
Available: In stock
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