Comparison

DENV2 (strain Thailand/16681/1984) Envelope Protein, His Tag (MALS & SPR verified) European Partner

Item no. ENN-D5243-500ug
Manufacturer ACROBiosystems
Amount 500 ug
Quantity options 500 ug 50 ug
Category
Type Proteins Recombinant
Format Solid
Specific against DENV (Dengue virus)
Host HEK293
Conjugate/Tag Unconjugated, HIS
Purity 90%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping condition Room temperature
Available
Specificity Dengue virus
Manufacturer - Category
Protein / Viral Proteins
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
65.0 kDa
Manufacturer - Format
Powder
Description
DENV2 (strain Thailand/16681/1984) Envelope Protein, His Tag (ENN-D5243) is expressed from human 293 cells (HEK293). It contains AA Phe 115 - Thr 280 & Met 281 - Ser 677 (Accession # P29990).
Background
Dengue is a mosquito-borne viral disease widely spread all over the world transmitted by 4 serotypes of dengue virus (DENV). The symptoms range from mild dengue fever to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with high mortality. Currently, most of the studies on DENV vaccines emphasize on its envelope protein which is essential for viral attachment and fusion (i.e., Sanofi’s tetravalent dengue vaccine Dengvaxia). However, the vaccine of envelope protein still needs to be improved to maximize its efficiency on people never infected with DENV before, which requires more research to be conducted on the DENV envelope protein.
Molecule
Envelope protein
Exp Region
Phe 115 - Thr 280 & Met 281 - Ser 677
Characteristics
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 65.0 kDa. The protein migrates as 60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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