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Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein (Monomer, MALS verified) European Partner

Item no. HLM-H82Ec-25ug
Manufacturer ACROBiosystems
Amount 25 ug
Quantity options 200 ug 25 ug
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Biotin, HIS, Avi
Purity 90%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag
C-10xHis, C-Avi, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
36.3 kDa and 11.7 kDa
Manufacturer - Format
Powder
Description
Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein (HLM-H82Ec) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & GLYDGMEHL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769 (B2M) & GLYDGMEHL).
Background
Melanoma-associated antigen A10 (MAGE-A10) is a cancer/testis protein associated with many cancers. MAGE-A10 is overexpressed in cancer cells. The repression of MAGE-A10 expression increased cell-cell and cell matrix adhesion. The Human HLA-A*0201 MAGE-A10 (GLYDGMEHL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and GLYDGMEHL peptide of the MAGE-A10.
Molecule
HLA-A*0201 & B2M & MAGE-A10 (GLYDGMEHL)
Exp Region
Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & GLYDGMEHL peptide
Characteristics
Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein is produced by co-expression of HLA and B2M loaded with MAGE-A10 peptide.This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).The protein has a calculated MW of 36.3 kDa and 11.7 kDa. The protein migrates as 40-43 kDa and 11 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 ug
Available: In stock
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