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(2R,3R)-E1R

(2R,3R)-E1R

Item no.	HY-116463C-25mg
Manufacturer	MedChem Express
CASRN	1400888-63-2
Amount	25 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.79
Citations	[1]Veinberg G, et al. Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor. Bioorg Med Chem. 2013 May 15;21(10):2764-71.
Smiles	O=C(N)CN1[C@H](C)[C@@H](C2=CC=CC=C2)CC1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Sigma Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	232.283
Product Description	(2R, 3R)-E1R (Compound 2b) is an enantiomer of E1R. (2R, 3R)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Neuronal Signaling
Isoform	Sigma 1 Receptor
Clinical information	No Development Reported

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HY-116463C-25mg-safety-datasheet.pdf