K00135

Item no.	HY-123141
Manufacturer	MedChem Express
CASRN	869650-21-5
Amount	1 ea
Quantity options	1 ea 10 mM / 1 mL 10 mg 1 mg 5 mg
Category	Food Safety Reagents & Chemicals Standards, Ladders & Markers Food Additives Acidity Regulators
Type	Standard
Specific against	other
Purity	98.03
Citations	[1]Pogacic V, et al. Structural analysis identifies imidazo [1, 2-b] pyridazines as PIM kinase inhibitors with in vitro antileukemic activity[J]. Cancer research, 2007, 67(14): 6916-6924.
Smiles	CC(C1=CC=CC(C2=CN=C3C=CC(NCC4CC4)=NN32)=C1)=O
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Category	Reference compound / Active compounds
Manufacturer - Targets	Pim
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	306.36
Product Description	K00135 is a potent and selective inhibitor of PIM kinases. K00135 inhibits survival and clonogenic growth of acute leukemia cells. K00135 inhibits the phosphorylation of PIM downstream targets[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 11.67 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	JAK/STAT Signaling
Clinical information	No Development Reported
UNSPSC Code	12352005

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