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HSP70-IN-1

HSP70-IN-1

Item no.	HY-12622-25mg
Manufacturer	MedChem Express
CASRN	1268273-90-0
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Neuroscience Neuroinflammation Protein Aggregation, Clearance & Misfolding By Cell Type Carcinoma Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.07
Citations	[1]Taldone T, et al. Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70. J Med Chem. 2014 Feb 27;57(4):1208-24.
Smiles	O=C(NC1=CC=CC(SC2=CN=C(N3CCN(C)CC3)N=C2OCC4=CC=CC=C4)=C1)CN
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	HSP
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	464.58
Product Description	HSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM.
Manufacturer - Research Area	Cancer
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Isoform	HSP70
Clinical information	No Development Reported

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HY-12622-25mg-safety-datasheet.pdf