Comparison

Paradol European Partner

Item no. HY-14617-1g
Manufacturer MedChem Express
CASRN 27113-22-0
Amount 1 g
Quantity options 100 mg 10 mM/1 mL 10 mg 1 g 25 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.87
Citations [1]van Breemen RB, et al. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011 Jan;82(1):38-43.|[2]Keum YS, et al. Induction of apoptosis and caspase-3 activation by chemopreventive [6]-paradol and structurally related compounds in KB cells. Cancer Lett. 2002 Mar 8;177(1):41-7.|[3]Gaire BP, et al. Neuroprotective effect of 6-paradol in focal cerebral ischemia involves the attenuation of neuroinflammatory responses in activated microglia. PLoS One. 2015 Mar 19;10(3):e0120203.|[4]Setoguchi S, et al. Pharmacokinetics of Paradol Analogues Orally Administered to Rats. J Agric Food Chem. 2016 Mar 9;64(9):1932-7.
Smiles COC1=C(O)C=CC(CCC(CCCCCCC)=O)=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias [6]-Gingerone,[6]-Paradol
Shipping Condition Room temperature
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
COX
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
278.39
Product Description
Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.
Manufacturer - Research Area
Cancer
Solubility
DMSO: ≥ 140 mg/mL
Manufacturer - Pathway
Immunology/Inflammation
Isoform
COX-2
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 g
Available: In stock
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