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Vatinoxan (hydrochloride)

Vatinoxan (hydrochloride)

Item no.	HY-19057A-50mg
Manufacturer	MedChem Express
CASRN	130466-38-5
Amount	50 mg
Quantity options	10 mMx1 mL 10 mg 25 mg 50 mg 5 mg
Category	Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.79
Citations	[1]Honkavaara JM, et al. The effects of increasing doses of MK-467, a peripheral alpha(2)-adrenergic receptor antagonist, on the cardiopulmonary effects of intravenous dexmedetomidine in conscious dogs. J Vet Pharmacol Ther. 2011 Aug;34(4):332-7.\|[2]Honkavaara J, et al. The effect of MK-467, a peripheral α2-adrenoceptor antagonist, on dexmedetomidine-inducedsedation and bradycardia after intravenous administration in conscious cats. Vet Anaesth Analg. 2017 Feb 22. pii: S1467-2987(16)31387-3.
Smiles	[H]Cl.CS(=O)(NCCN([C@]1(CN2)CCN3CCC4=C(OC5=CC=CC=C54)[C@]3([H])C1)C2=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MK-467 (hydrochloride),L-659066 (hydrochloride)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Adrenergic Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen)
Molecular Weight	454.97
Product Description	Vatinoxan hydrochloride (MK-467 hydrochloride; L-659066 hydrochloride) is a peripheral α2 adrenergic receptor antagonist.
Manufacturer - Research Area	Neurological Disease; Endocrinology
Solubility	DMSO: 10 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	α adrenergic receptor
Clinical information	No Development Reported

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HY-19057A-50mg-safety-datasheet.pdf