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3-(3-Hydroxyphenyl)propionic acid European Partner

Item no. HY-W005255-10mM
Manufacturer MedChem Express
CASRN 621-54-5
Amount 10 mM/1 mL
Quantity options 10 mM/1 mL 1 g 500 mg 5 g
Category
Type Inhibitors
Specific against other
Purity 99.89
Citations [1]Najmanová I, et al. Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rats. Mol Nutr Food Res. 2016 May;60(5):981-91.
Smiles O=C(O)CCC1=CC=CC(O)=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
Neuroscience-Neuromodulation
Manufacturer - Targets
Endogenous Metabolite
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
166.18
Product Description
3-(3-Hydroxyphenyl)propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3-(3-Hydroxyphenyl)propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3-(3-Hydroxyphenyl)propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3-(3-Hydroxyphenyl)propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases[1].
Manufacturer - Research Area
Cardiovascular Disease
Solubility
DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Metabolic Enzyme/Protease
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mM/1 mL
Available: In stock
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