Comparison

Monoclonal Anti-SN38 Antibody, Mouse IgG1 European Partner

Item no. SN8-M685-1mg
Manufacturer ACROBiosystems
Amount 1 mg
Quantity options 100 ug 1 mg
Category
Type Proteins Recombinant
Format Solid
Applications ELISA, IA
Specific against Mouse (Murine, Mus musculus)
Host HEK293
Isotype IgG1
Conjugate/Tag Unconjugated
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping Condition Room temperature
Available
Manufacturer - Category
Antibody / Recombinant Antibodies
Manufacturer - Conjugate / Tag
Mouse IgG1 | Mouse kappa, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Manufacturer - Format
Powder
Description
The 7-ethyl-10-hydroxycamptothecin (SN-38) is a topoisomerase I inhibitor (chemotherapeutic agent) used in cancer therapy. In a comparative study of SN-38 with a potent chemotherapeutic prodrug, irinotecan (CPT-11), SN-38 was found to be 1000-fold more cytotoxic against colorectal cancer cells as compared to irinotecan.
Background
The 7-ethyl-10-hydroxycamptothecin (SN-38) is a topoisomerase I inhibitor (chemotherapeutic agent) used in cancer therapy. In a comparative study of SN-38 with a potent chemotherapeutic prodrug, irinotecan (CPT-11), SN-38 was found to be 1000-fold more cytotoxic against colorectal cancer cells as compared to irinotecan.
Molecule
SN38
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower._x000D_Please avoid repeated freeze-thaw cycles.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
available

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