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Mouse Anti Human CD11b

Mouse Anti Human CD11b

Item no.	ant-274-0.5mg
Manufacturer	ProSpec
Amount	0.5mg
Category	Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies Primary Antibodies Oligodendrocyte Markers
Type	Antibody Monoclonal
Clone	hCD11b
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Synonyms	Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b antigen, ITGAM, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044
Introduction	Integrins are heterodimeric integral membrane proteins consisting of an chain and a chain. CD11b is an I-domain including integrin combines with the 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor also called MAC1. The M beta 2 integrin is crucial in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Immunogen	Purified human PBL Monocytes.
Purification Method	Ion exchange column.
Protein concentration	1mg/ml in PBS (after reconstitution)
Antibody Properties	Blocking and staining antibody. For staining, use 10ul/1, 000, 000 cells. Titer for blocking LPS binding should be determined by the investigator.
Available Conjugates	This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10ul/106 cells.
Reconstitution	Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Storage	Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 8/21/2025

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