IL17A

Item no.	cyt-250-1mg
Manufacturer	ProSpec
Amount	1 mg
Quantity options	1 mg 25 ug 5 ug
Category	Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 95.0% as determined by SDS-PAGE.
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	IL 17A,CTLA-8,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8
Similar products	IL 17
Available
Manufacturer - Category	CYTOKINES AND GROWTH FACTORS
Storage Conditions	Lyophilized Interleukin 17A although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution IL17 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description	Recombinant Human Interleukin-17A
Formulation	Sterile filtered lyophilized (freeze-dried) powder, with 20mM Citrate, 0.1M NaCl, pH4.5.
Introduction	IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Biological Activity	The ED50 as determined by the dose-dependent induction of IL-6 in Hs68 cell line was found to be approximately 2ng/ml corresponding to a Specific Activity of 500, 000IU/mg.
Manufacturer - Format	Sterile Filtered White lyophilized (freeze-dried) powder.

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cyt-250-1mg-safety-datasheet.pdf