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HSD17B8

HSD17B8

Item no.	enz-108-20ug
Manufacturer	ProSpec
Amount	20 ug
Quantity options	1 mg 20 ug 5 ug
Category	Food Safety Hormones Peptides & Proteins Enzymes
Type	Enzymes
Format	Liquid
Specific against	Human (Homo sapiens)
Purity	Greater than 95.0% as determined by SDS-PAGE.
Sequence	MGSSHHHHHH SSGLVPRGSH MASQLQNRLR SALALVTGAG SGIGRAVSVR LAGEGATVAA CDLDRAAAQE TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV VSCAGITQDE FLLHMSEDDW DKVIAVNLKG TFLVTQAAAQ ALVSNGCRGS IINISSIVGK VGNVGQTNYA ASKAGVIGLT QTAARELGRH GIRCNSVLPG FIATPMTQKV PQ
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	HSD17B8,Estradiol 17-beta-dehydrogenase 8,17-beta-hydroxysteroid dehydrogenase 8,17-beta-HSD 8,3-oxoacyl-[acyl-carrier-protein] reductase,Protein Ke6,Ke-6,Really interesting new gene 2 protein,Testosterone 17-beta-dehydrogenase 8,HSD17B8,FABGL,HKE6,RING2,KE6,FABG,H2-KE6,SDR30C1,D6S2245E,dJ1033B10 9
Similar products	HSD17B8
Available
Manufacturer - Category	ENZYMES
Storage Conditions	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Description	Recombinant Human Hydroxysteroid (17-beta) Dehydrogenase 8
Formulation	HSD17B8 solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 40% glycerol and 150mM NaCl.
Introduction	Estradiol 17-beta-dehydrogenase 8 (HSD17B8) is a member of the short-chain dehydrogenases/reductases (SDR) family. In mice, the HSD17B8 protein is a 17-beta-hydroxysteroid dehydrogenase which can regulate the concentration of biologically active estrogens and androgens. HSD17B8 is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the HSD17B8 enzyme has some reductive activity and can synthesize estradiol from estrone. HSD17B8 may have a role in biosynthesis of fatty acids in mitochondria.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile filtered colorless solution.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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enz-108-20ug-safety-datasheet.pdf